Clinical Course of Hyperprolactinemia in Children .pdf


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H, IM
IM
G
G, PA
IM
None
IM
IM

17.9

16.0
16.1

14.2

16.8

17.1

16.1

16.8

IRA/Sulphasalasine

-

Depression/
Sertraline, Hydroxine

Hirsutism/OC

Depression/
Risperidone, Paroxetine
-

-

-

-

-

-

Depression/
Alprazolam, Sulpiride

Depression/
Risperidone, Sertraline

Obesity, hirsutism/
Cyproterone acetate, OC

-

-

Coexisting disease/
drug use

67

85

185

63

201

99
99.85

126

448

1677

49.6

283

200

88.7

51.1

598

87

Initial prolactin
ng/mL

normal MRI

Microadenoma

Antipsychotic medication,
microadenoma

Microadenoma

Microadenoma

Partial empty sella
Antipsychotic medication

Microadenoma

Microadenoma

Macroadenoma

Microoadenoma

Macroadenoma

Antipsychotic medication

Antipsychotic medication

Possible microadenoma

Macroadenoma

Possible microadenoma

Diagnosis

No

No

No

No

No

No
No

No

No

Yes

No

Yes

No

No

No

Yes

No

H
G

Randomly

14.1

13.0

-

-

-

-

Coexisting disease/
drug use

H: headache, G: galactorrhea, BV: blurred vision, B: bromcriptine, C: cabergoline

H, BV

8.5

Clinical
presentation

16.1

Age (years)

576

396

2300

2000

Initial prolactin
ng/mL

Macroadenoma

Macroadenoma

Macroadenoma

Macroadenoma

Diagnosis

Table 3b. Age, diagnosis, clinical presentation, prolactin level, and treatment modes of male hyperprolactinemia patients

B: bromcriptine, C: cabergoline

Yes

Pituitary surgery

Yes

Yes

Yes

B

B

B

Treatment

B

B

C

C

Treatment

B

B

B

C

B

B
B

B

C

C

C

Recovery after operation

Recovery after cessation of
antipsychotic drug

B, Recovery after cessation of
antipsychotic drug

Pituitary surgery

H: headache, G: galactorrhea, PA: primary amenorrhea, IM: irregular menstruation, BV: blurred vision, OC: Oral contraceptive, IRA: Idiopathic rheumatoid arthritis,

G, IM

13.0

G, PA

16.9
IM

G, IM

15.9

PA

None

15.6

16.3

IM

16.3

17.6

H

H, G, PA

14.5

Clinical
presentation

7.4

Age (years)

Table 3a. Age, diagnosis, clinical presentation, prolactin level, and treatment modes of female hyperprolactinemia patients

Eren E et al.
Prolactin and Children

67


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