TempVapo .pdf
Nom original: TempVapo.pdfTitre: JCANT 1(3-4) Case.vpAuteur: JGlover
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John M. McPartland and Ethan B. Russo
111
FIGURE 1. Phytocannabinoids
Structure*
Concentration†
(% dry weight)
Boiling
Point °C§
Properties
Δ-9-tetrahydrocannabinol (THC)
0.1-25%
157
Euphoriant
Analgesic
Antiinflammatory
Antioxidant
Antiemetic
0.1-2.89%
160-180
Anxiolytic
Analgesic
Antipsychotic
Antiinflammatory
Antioxidant
Antispasmodic
0.0-1.6%
185
Oxidation
breakdown
product
Sedative
Antibiotic
0.0-0.65%
220
Antiinflammatory
Antibiotic
Antifungal
0.03-1.15%
MP
52
Antiinflammatory
Antibiotic
Antifungal
CH3
OH
CH3
H3C
O
cannabidiol (CBD)
CH3
OH
CH2
OH
CH3
cannabinol (CBN)
CH3
OH
CH3
CH3
O
cannabichromene (CBC)
OH
O
cannabigerol (CBG)
OH
HO
112
CANNABIS THERAPEUTICS IN HIV/AIDS
FIGURE 1 (continued)
Structure*
Concentration†
(% dry weight)
Boiling
Point °C§
Properties
Δ-8-tetrahydrocannabinol (Δ-8-THC)
0.0-0.1%
175-178
Resembles
Δ-9-THC
Less psychoactive
More stable
Antiemetic
0.0-1.36%
< 220
Analgesic
Euphoriant
CH3
OH
CH3
H3C
O
tetrahydrocannabivarin (THCV)
OH
O
John M. McPartland and Ethan B. Russo
113
FIGURE 2. Terpenoid essential oil components of cannabis.
Cannabis Constituent Structure*
Concentration†
Boiling
Point °C§
Properties
β-myrcene
0.47%
166-168
Analgesic
Antiinflammatory
Antibiotic
Antimutagenic
β-caryophyllene
0.05%
119
Antiinflammatory
Cytoprotective
(gastric mucosa)
Antimalarial
d-limonene
0.14%
177
Cannabinoid agonist?
Immune potentiator
Antidepressant
Antimutagenic
0.002%
198
Sedative
Antidepressant
Anxiolytic
Immune potentiator
0.001%
224
Memory booster?
AChE inhibitor
Sedative
Antipyretic
> 0.001%
176
AChE inhibitor
Increases cerebral
blood flow
Stimulant
Antibiotic
Antiviral
Antiinflammatory
Antinociceptive
0.04%
156
Antiinflammatory
Bronchodilator
Stimulant
Antibiotic
Antineoplastic
AChE inhibitor
H
linalool
HO
pulegone
O
1,8-cineole (eucalyptol)
O
α-pinene
114
CANNABIS THERAPEUTICS IN HIV/AIDS
FIGURE 2 (continued)
Cannabis Constituent Structure*
Concentration†
Boiling
Point °C§
Properties
α-terpineol
0.02%
217-218
Sedative
Antibiotic
AChE inhibitor
Antioxidant
Antimalarial
0.0004%
209
AChE inhibitor
Antibiotic
p-cymene
0.0004%
177
Antibiotic
Anticandidal
AChE inhibitor
borneol
0.008%
210
Antibiotic
0.004%
168
Antiinflammatory
OH
terpineol-4-ol
OH
OH
Δ-3-carene
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