Abstracts from CIPP XVI Meeting Libon june 2017.pdf


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DOI: 10.1002/ppul.23731

ABSTRACT

Abstracts from CIPP XVI Meeting
VII. POSTERS

was 1.99 (95% CI 1.53–2.56) and the adjusted OR was 1.86 (95%
CI 1.23–2.80). DISCUSSION: the determination of wheezing in

A . BRO NC H I A L AS TH M A AN D O TH E R
C H R O N I C OB S T R U C T I V E P U L M O N A R Y
DISEASES

infants and preschool children exclusively by written questionnaire
is inaccurate and in agreement with Michel et al.(4) and Cane and
McKenzie(5). Among adolescents, the written questionnaire has
acceptable accuracy. This difference with our study can be justified

#A14 − Accuracy of Wheezing in Infants and Preschool
Children by Written Questionnaire.
1

1

by the greater expertise of teenagers’ parents. Thus, the video
questionnaire is a necessary tool in determining wheezing in
preschool children and possibly in infants whose parents are even

1

2

Espíndola Filho MA , Silva WC , Cavalcanti ET , Melo EP ,
Bezerra PG 2, Britto MC 3
Medicina, Faculdade Pernambucana de Saúde − Recife, Brazil; 2Pneumologia
pediátrica, Instituto de Medicina Integral Prof. Fernando Figueira − Recife, Brazil;
3
Pediatric Pulmonology, Instituto de Medicina Integral Prof. Fernando Figueira −
Recife, Brazil
1

less experienced.
References
1. Mallol J and the EISL Study Group. International prevalence of
recurrent

wheezing

during

the

first

year

of

life.

Thorax

2010;65:1004–09. 2. Lai C et al. Global variation in the prevalence
Introduction

and severity of asthma symptoms. Thorax. 2009;64:476–83. 3.
Collins SA and Southampton Women’s Survey Study Group.

The prevalence of wheezing in preschool children is unknown. In

Validation of novel wheeze phenotypes in the first 6 years of life.

school children, prevalence is between 2–38%.(1) Epidemiological

Pediatr Pulmonol. 2013;48:683–692. 4. Michel G et al. Parental

studies are based on information provided by parents.(2,3)

understanding of wheeze and its impact on asthma prevalence

However, it is often inadequate and video questionnaires may

estimates. ERJ. 2006;28:1124–30. 5. Cane RS, McKenzie SA.

be an alternative. Two studies showed that a significant proportion

Parents’ interpretations of children’s respiratory symptoms on

of cases are inaccurate.(4,5). This study aimed to determine the

video. ADC. 2001;84:31–34.

perception of wheezing by the caregivers of infants and
preschoolers compared with the video. METHODS: a crosssectional study with infants and preschoolers was performed at
the IMIP, in Brazil, between January and June 2016, with

#A24 – Severe Asthma and Bronchiolitis Obliterans in

scheduled appointments for any complaint and no exclusion

Children and Adolescents: How to Differentiate with

criteria. A researcher first applied the written questionnaire,

regard to Tomographic, Functional and Inflammation

then exhibited a video of a baby with wheezing on a tablet and

Aspects?

applied the second questionnaire. Data analysis was performed
using SAS version 8. The Generalized Estimation Equations method

Fernandes RV
Universidade Federal de Goiàs, Goiânia, Brazil

was used for confounders. The project was approved by the ethics
committee (number 5554). RESULTS: of the 196 interviews, the
median age of the caregivers was 28.5 years, 182 were female and

Introduction

only 109 studied >8 years. In the written questionnaire, 100

Treatment-resistant severe asthma (TRSA) and post-infectious

(51.0%) of the children had experienced wheeze in their lifetime,

bronchiolitis obliterans (PIBO) are obstructive pulmonary diseases

58 (59.8%) had ≤ 3 episodes/year, 124 (63.3%) had previous

whose characteristics can overlap and, in some cases, even with

breathlessness and 69 (66.9%) had ≤ 3 episodes/year. Twenty-

clinical history data, pulmonary function and tomography, the

seven (13%) had diagnosed asthma, 120 presented snoring and 87

differential diagnosis can be difficult. In addition, no exclusively

had stridor. After the video, 67 (34.2%) of the children had

pediatric study has compared both of these diseases. Objective:

wheezing at least once in their lives, and 57 (85.1%) had up to three

Identify which alterations in lung function, tomography and

episodes/year. Seventy-six (38.8%) had had dyspnea, of which 59

exhaled nitric oxide (ENO), induced sputum cellularity, IgE and

(77.6%) had ≤ 3 episodes/year. In multivariate analysis, the written

allergic tests allow differentiating TRSA and PIBO in children and

questionnaire had a slight influence on confounders. The crude OR

adolescents.

S100

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© 2017 Wiley Periodicals, Inc.

wileyonlinelibrary.com/journal/ppul

Pediatric Pulmonology. 2017;52:S100–S176.