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Job Description temp Kymab Assay team 100%

Job Description Research Associate in Antibody Discovery and Therapeutic Targets Research Associate in the Antibody Discovery Group reporting to Group Leader Assay Team Antibody Discovery 12 months fixed term contract Job description:

https://www.fichier-pdf.fr/2014/11/20/job-description-temp-kymab-assay-team/

20/11/2014 www.fichier-pdf.fr

201700000910 Gilquin B 99%

Proteomics 17, 1–2, 2017, 1600357 (1 of 5) 1600357 DOI 10.1002/pmic.201600357 TECHNICAL BRIEF A proteomics assay to detect eight CBRN-relevant toxins in food Benoit Gilquin1,2,3,4 , Michel Jaquinod1,2,3 , Mathilde Louwagie1,2,3 , Sylvie Kieffer-Jaquinod1,2,3 , Alexandra Kraut1,2,3 , Myriam Ferro1,2,3 , Franc¸ois Becher5 and Virginie Brun1,2,3 1 Universite´ Grenoble-Alpes, Grenoble, France CEA, BIG, Biologie a` Grande Echelle, Grenoble, France 3 INSERM, U1038, Grenoble, France 4 CEA, LETI, Clinatec, Grenoble, France 5 ´ ´ CEA, iBiTec-S, Laboratoire d’Etude du Metabolisme des Medicaments, Gif-sur-Yvette, France 2 A proteomics assay was set up to analyze food substrates for eight toxins of the CBRN (chemical, biological, radiological and nuclear) threat, namely ricin, Clostridium perfringens epsilon toxin (ETX), Staphylococcus aureus enterotoxins (SEA, SEB and SED), shigatoxins from Shigella dysenteriae and entero-hemorragic Escherichia coli strains (STX1 and STX2) and Campylobacter jejuni cytolethal distending toxin (CDT).

https://www.fichier-pdf.fr/2018/07/19/201700000910-gilquin-b/

19/07/2018 www.fichier-pdf.fr

rapport 1 modif pdf 95%

Test Details Methodology This assay is performed on extracted DNA.

https://www.fichier-pdf.fr/2017/01/24/rapport-1-modif-pdf/

24/01/2017 www.fichier-pdf.fr

protozoaires 92%

Rapid immunochromatographic cartridge assay A rapid cartridge is available that detects antigens of E.

https://www.fichier-pdf.fr/2017/01/22/protozoaires/

22/01/2017 www.fichier-pdf.fr

201700000916 Gilquin B 90%

This article presents the development of a targeted proteomic assay to quantify 4 acute kidney injury biomarker candidates in urine samples.

https://www.fichier-pdf.fr/2018/07/19/201700000916-gilquin-b/

19/07/2018 www.fichier-pdf.fr

45643 SZBD294XV 88%

The estimated uncertainty of a single measurement of the assay can be expected to be 1 % relative (confidence level = 95%, n= 6) whereby the assay measurements are calculated by 100% minus found impurities.

https://www.fichier-pdf.fr/2017/02/16/45643-szbd294xv/

16/02/2017 www.fichier-pdf.fr

10-Moron-JNeurosci2002 86%

This assay allows us to dissociate changes in extracellular DA that result from altered DA clearance from changes that result from altered DA release, which can be secondary to elevations in NE or 5-HT (Pozzi et al., 1994, 1999;

https://www.fichier-pdf.fr/2011/09/28/10-moron-jneurosci2002/

28/09/2011 www.fichier-pdf.fr

biblio covid19 3 83%

A Report of 1014 Cases Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT POINTS CLES The positive rates of RT-PCR assay and chest CT imaging in our cohort were 59% (601/1014), and 88% (888/1014) for the diagnosis of suspected patients with COVID-19, respectively.

https://www.fichier-pdf.fr/2020/03/26/bibliocovid193/

26/03/2020 www.fichier-pdf.fr

CRISP CHINE 2 82%

Off-target cleavage was also apparent in these 3PN zygotes as revealed by the T7E1 assay and whole-exome sequencing.

https://www.fichier-pdf.fr/2016/02/27/crisp-chine-2/

27/02/2016 www.fichier-pdf.fr

Am. J. Epidemiol.-1996-Ferrini-642-4 82%

For estradiol and bioavailable estradiol, 14 percent (101 of 728 women) had values below the sensitivity of the assay.

https://www.fichier-pdf.fr/2010/11/26/am-j-epidemiol-1996-ferrini-642-4/

26/11/2010 www.fichier-pdf.fr

Antimicrobial properties of extracts regions of Tunisia 80%

COMBINATION WITH PLANT EXTRACTS IMPROVES THE INHIBITORY ACTION OF DIVERGICIN M35 AGAINST LISTERIA MONOCYTOGENES ABDEL-MAJEED ZOUHIR1, EHAB KHEADR2,3, IMANE TAHIRI2, JEANNETTE BEN HAMIDA1 and ISMAIL FLISS2,4 1 Unité de Protéomie Fonctionnelle et Biopréservation Alimentaire ISSBAT Tunis, Tunisia 2 Dairy Research Center STELA Nutraceuticals and Functional Foods Institute (INAF) Laval University Quebec, PQ, Canada, G1K 7P4 3 Department of Dairy Science and Technology Faculty of Agriculture University of Alexandria Alexandria, Egypt Accepted for Publication July 24, 2007 ABSTRACT The susceptibility of 11 strains of Listeria monocytogenes to divergicin M35, a bacteriocin produced by Carnobacterium divergens strain M35, and to aqueous extracts of garlic, onion, oregano, red chili and black pepper at 30 and 10C, was evaluated using a microdilution assay.

https://www.fichier-pdf.fr/2013/09/07/antimicrobial-properties-of-extracts-regions-of-tunisia/

07/09/2013 www.fichier-pdf.fr

effects on neuron 79%

Using these cultures, an excitatory Ca2+influx assay was employed as an indicator of neural physiological activity.

https://www.fichier-pdf.fr/2017/09/10/effects-on-neuron/

10/09/2017 www.fichier-pdf.fr

PhD position Le Clainche I2BC 79%

To this aim, he/she will adapt the microscopy assay that we developed to reconstitute the actomyosin-dependent talin-vinculin mechanosensitive complex with pure proteins on geometrically-defined micropatterned surfaces (Ciobanasu et al, 2014 Nature Communications;

https://www.fichier-pdf.fr/2016/10/24/phd-position-le-clainche-i2bc/

24/10/2016 www.fichier-pdf.fr

2017-08 ad for biochemist position f 78%

A mix of standard (colorimetric assay, light scattering or SPR, TEM…) and advanced (fluorescent tagging for live in vitro assay on TIRF microscopy, AFM…) approaches will be used, in order to set up a standardized procedure for phenotypic characterization.

https://www.fichier-pdf.fr/2017/08/14/2017-08-ad-for-biochemist-position-f/

14/08/2017 www.fichier-pdf.fr

section 6 78%

The singlecell gel electrophoresis (comet assay) has been widely used to determine DNA damages:

https://www.fichier-pdf.fr/2012/01/17/section-6/

17/01/2012 www.fichier-pdf.fr

ijc30720 77%

Proliferation assay.

https://www.fichier-pdf.fr/2017/05/06/ijc30720/

06/05/2017 www.fichier-pdf.fr

Giresi2006 GenomeResearch FAIRE 74%

Both little signal from either assay as one techniques isolate DNA fragments flanking DNaseI cleavage sites and map them back to the genome moved away from the proximal prousing microarrays (Crawford et al.

https://www.fichier-pdf.fr/2010/10/16/giresi2006-genomeresearch-faire/

16/10/2010 www.fichier-pdf.fr

nprot.2011.396 73%

The protocol is compatible with the SOLiD sequencing platform and allows simultaneous enrichment of three to five samples for a human whole-exome capture (38 or 50 Mb, respectively), 20 samples for a medium-sized design (5 Mb) or 96 samples for a 0.4-Mb target in a single assay.

https://www.fichier-pdf.fr/2012/03/10/nprot-2011-396/

10/03/2012 www.fichier-pdf.fr

immuno-hématologie 71%

Enzyme Linked Immunosorbent Assay HBs :

https://www.fichier-pdf.fr/2018/12/08/immuno-hematologie/

08/12/2018 www.fichier-pdf.fr

D Article partie 3 Doc TD 25092017 69%

One unit of PPO activity was defined as the increase of 0.01 in absorbance per min under assay conditions.

https://www.fichier-pdf.fr/2017/10/11/d-article-partie-3-doc-td-25092017/

11/10/2017 www.fichier-pdf.fr

CQI Vircell - ORGENTEC SASU 68%

Ideal for the ĚĂŝůLJ ĐŽŶƚƌŽů of molecular assays and instrument performance to aid ůĂďŽƌĂƚŽƌŝĞƐ ŝŶ ŵĞĞƟŶŐ ƋƵĂůŝƚLJ ĂŶĚ ƌĞŐƵůĂƚŽƌLJ ƌĞƋƵŝƌĞŵĞŶƚƐ͘ Controls that contain the ĐŽŵƉůĞƚĞ ŝŶĂĐƟǀĂƚĞĚ ŵŝĐƌŽŽƌŐĂŶŝƐŵ in a matrix that ŵŝŵŝĐƐ ŚƵŵĂŶ ƐƉĞĐŝŵĞŶƐ to ensure consistent, accurate and meaningful test results, avoiding the risk of ƵƐŝŶŐ ŝŶĨĞĐƟŽƵƐ ĂŐĞŶƚƐ͘ >LJŽƉŚŝůŝnjĞĚ ƉƌĞƐĞŶƚĂƟŽŶ to ensure stability ĂŶĚ ĂǀŽŝĚ ĞdžƚƌĂ ƚƌĂŶƐƉŽƌƚ ĐŽƐƚƐ͘ IVD dŚĞ ĐƵƌƌĞŶƚ ƚƌĞŶĚ ŝŶ ƚŚĞ ĚŝĂŐŶŽƐŝƐ ŽĨ ŝŶĨĞĐƟŽƵƐ ĚŝƐĞĂƐĞƐ ŵŽǀĞƐ ƚŽǁĂƌĚƐ ŵŽƌĞ ƐƉĞĐŝĮĐ ĂŶĚ ƐĞŶƐŝƟǀĞ ĐƵƫŶŐ ĞĚŐĞ ƚĞĐŚŶŝƋƵĞƐ ĨŽƌ ŶƵĐůĞŝĐ ĂĐŝĚƐ ĚĞƚĞĐƟŽŶ ƚŽ ŽďƚĂŝŶ ĨĂƐƚĞƌ ĚŝĂŐŶŽƐŝƐ͘ >ĂďŽƌĂƚŽƌŝĞƐ ĂƌŽƵŶĚ ƚŚĞ ǁŽƌůĚ ĨĂĐĞ ƚŚĞ ĐŚĂůůĞŶŐĞ ŽĨ ŝŵƉůĞŵĞŶƟŶŐ ŶĞǁ E ĂŵƉůŝĮĐĂƟŽŶ ƚĞƐƚƐ ĂŶĚ ĮŶĚŝŶŐ ĚĞƉĞŶĚĂďůĞ͕ ĐŽŶǀĞŶŝĞŶƚ ĂŶĚ ĂīŽƌĚĂďůĞ ƋƵĂůŝƚLJ ĐŽŶƚƌŽů ŵĂƚĞƌŝĂů ƚŽ ŵŽŶŝƚŽƌ ĂƐƐĂLJ ĂŶĚ ŝŶƐƚƌƵŵĞŶƚ ƉĞƌĨŽƌŵĂŶĐĞ ƉƌŝŽƌ ƚŽ ƌĞƉŽƌƟŶŐ ƉĂƟĞŶƚ ƌĞƐƵůƚƐ͘ ŶŚĂŶĐĞ ƚŚĞ ƋƵĂůŝƚLJ ŽĨ ƚŚĞ ǁŚŽůĞ ƚĞƐƟŶŐ ƉƌŽĐĞƐƐ͗ ĞdžƚƌĂĐƟŽŶ ĂŶĚ ĂŵƉůŝĮĐĂƟŽŶ DŽŶŝƚŽƌ Ăůů ĂƐƉĞĐƚƐ ŽĨ ƐĂŵƉůĞ ƚĞƐƟŶŐ ĂŶĚ ŝŶƐƚƌƵŵĞŶƚ performance in the long term DŽŶŝƚŽƌ ǀĂƌŝĂƟŽŶƐ ŝŶ ůĂďŽƌĂƚŽƌLJ ƉƌŽĐĞĚƵƌĞƐ͕ ŝŶĐůƵĚŝŶŐ batches of assay reagents Validate and verify new assays Obtain reliable and comparable results Train laboratory personnel/ trial purposes dĂŬĞ ĐŽƌƌĞĐƟǀĞ ĂĐƟŽŶƐ ƉƌŝŽƌ ĂƐƐĂLJ ĨĂŝůƵƌĞ ĂŶĚ ĚĞƚĞĐƚ ĂŶĚ troubleshoot suspect results ŽŵƉůLJ ǁŝƚŚ ůĂď ĂĐĐƌĞĚŝƚĂƟŽŶ ƌĞƋƵŝƌĞŵĞŶƚƐ ŝīĞƌĞŶƟĂů ĨĞĂƚƵƌĞƐ͗ Whole pathogen controls with complete genome Monodose format YƵĂŶƟĮĞĚ ĐŽŶƚƌŽůƐ ;ůŽǁ ƉŽƐŝƟǀĞͿ >LJŽƉŚŝůŝnjĞĚ ƉƌĞƐĞŶƚĂƟŽŶ ƚŽ ĞŶƐƵƌĞ ƐƚĂďŝůŝƚLJ ĂŶĚ avoid extra transport costs Validated with the most commonly used ĞdžƚƌĂĐƟŽŶ ƉůĂƞŽƌŵƐ ;ŵĂŶƵĂů Θ ĂƵƚŽŵĂƟĐͿ CE marked products <ŝƚ ĐŽŶƚĞŶƚƐ͗ ϭϬ ǀŝĂůƐ ǁŝƚŚ ůLJŽƉŚŝůŝnjĞĚ ŝŶĂĐƟǀĂƚĞĚ ĐŽŵƉůĞƚĞ pathogens in a matrix Ăƚ͘ EŽ͘ ĞƐĐƌŝƉƟŽŶ D d ϬϮϮ DW>/ZhEΠ dKd >

https://www.fichier-pdf.fr/2016/06/09/cqi-vircell-orgentec-sasu/

09/06/2016 www.fichier-pdf.fr