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Scaffold-supported, reprogrammed neuronal networks were successfully grafted into organotypic hippocampal brain slices, showing an B3.5-fold improvement in neurite outgrowth and increased action potential firing relative to injected isolated cells.

2011 Acetonic Extract of Buxus sempervirens Induces Cell Cycle Arrest, Apoptosis and Autophagy in Breast Cancer Cells Acetonic Extract of Buxus sempervirens Induces Cell Cycle Arrest, Apoptosis and Autophagy in Breast Cancer Cells Ouardia Ait-Mohamed1*, Valentine Battisti2, Ve´ronique Joliot2, Lauriane Fritsch2, Julien Pontis2, Souhila Medjkane2, Catherine Redeuilh3, Aazdine Lamouri3, Christine Fahy3, Mohamed Rholam3, Djebbar Atmani1, Slimane Ait-Si-Ali2* 1 Laboratoire de Biochimie Applique´e, Faculte´ des Sciences de la Nature et de la vie, Universite´ de Be´jaia, Be´jaia, Algeria, 2 Laboratoire Epige´ne´tique et Destin Cellulaire, UMR7216, Centre National de la Recherche Scientifique (CNRS), Universite´ Paris Diderot Sorbonne Paris Cite´, Paris, France, 3 Laboratoire ITODYS, UMR7086 CNRS, Universite´ Paris Diderot Sorbonne Paris Cite´, Paris, France Abstract Plants are an invaluable source of potential new anti-cancer drugs.

Adaptive immune cells intial innate response © 2007 Nature Publishing Group http://www.nature.com/naturemedicine LETTERS Adaptive immune cells temper initial innate responses Kwang Dong Kim1–3, Jie Zhao1,3, Sogyong Auh2, Xuanming Yang1, Peishuang Du1, Hong Tang1 &

Highlights d The capacity of human muscle stem cells to enter quiescence diminishes with age d This reduced capacity to re-quiesce is associated with increased DNA methylation d DNA methylation suppresses SPRY1, a known regulator of quiescence d Senescence, a feature of late cell division counts, is not increased with age Bigot et al., 2015, Cell Reports 13, 1172–1182 November 10, 2015 ª2015 The Authors http://dx.doi.org/10.1016/j.celrep.2015.09.067 Accession Numbers GSE52699 GSE53302 Cell Reports Article Age-Associated Methylation Suppresses SPRY1, Leading to a Failure of Re-quiescence and Loss of the Reserve Stem Cell Pool in Elderly Muscle Anne Bigot,1,4 William J.

2004, 76, 483-488 Transport, Location, and Quantal Release Monitoring of Single Cells on a Microfluidic Device Wei-Hua Huang,† Wei Cheng,† Zhen Zhang,† Dai-Wen Pang,† Zong-Li Wang,† Jie-Ke Cheng,*,† and Da-Fu Cui‡ Department of Chemistry, Wuhan University, Wuhan 430072, China, and State Key Laboratories of Transducer Technology, The Institute of Electronics, Chinese Academy of Science, Beijing 100080, China A novel microfluidic device has been developed for onchip transport, location, and quantal release monitoring of single cells.

2013 Macmillan Publishers Limited All rights reserved 0950-9232/13 www.nature.com/onc ORIGINAL ARTICLE Mitochondrial dynamics regulates migration and invasion of breast cancer cells J Zhao1,2,3, J Zhang1,3, M Yu1,3, Y Xie2, Y Huang1, DW Wolff2, PW Abel2 and Y Tu2 Mitochondria are highly dynamic and undergo constant fusion and fission that are essential for maintaining physiological functions of cells.

Our data substantiate a new role for mitochondrial dynamics and suggest that mitochondria redistribution is required to regulate the motor of migrating cells.

They are biotrophic parasites that can induce the (re)differentiation of either differentiated or undifferentiated plant cells into specialized feeding cells.

PPP Master1 Induction of Epithelial to Mesenchymal Transition via the Slug Pathways is Triggered by the Secretome of Senescent Cells Grimaud Joaquim, Prouteau Clément, Aceti-Fritsch Pierre-André, Larochette Vincent.

the routes taken by immune cells that patrol the meninges under healthy conditions and invade the parenchyma during pathology;

Histological examination and immunohistochemical staining revealed that the mass was composed mostly of cysts lined by respiratory epithelium, submucosal glands with goblet cells, and intervening nerve twigs.

price new 2013 2 Cairo comp cairocomp FGB IT.

François Féron Journal of Visualized Experiments www.jove.com Video Article Isolating Nasal Olfactory Stem Cells from Rodents or Humans 1,2 3 1,2,4 Stéphane D.

Art1 OPA3 F actin migration PlosOne13 Downregulation of OPA3 Is Responsible for Transforming Growth Factor-b-Induced Mitochondrial Elongation and F-Actin Rearrangement in Retinal Pigment Epithelial ARPE-19 Cells Seung-Wook Ryu1,2*, Jonghee Yoon1, Nambin Yim1, Kyungsun Choi1, Chulhee Choi1,2* 1 Department of Bio and Brain Engineering, KAIST, Daejeon, Korea, 2 KI for the Biocentury, KAIST, Daejeon, Korea Abstract Transforming growth factor-b signaling is known to be a key signaling pathway in the induction of epithelial–mesenchymal transition.

15 July 2020 Memory T cells induced by previous pathogens can shape the susceptibility to, and clinical severity of, subsequent infections1.

cervical carcinoma HeLa, immortalized lymphoblast GM06690 (GM), leukaemia K562, embryonic stem cells (ES) and BMP4-induced ES cells (dES).

The purpose of this work was the investigation of a three-dimensional nanointerface, enabling simultaneous guidance and recording of electrogenic cells (HL-1) by utilizing nanostructures with a mushroom shape on MEAs.

Several pre-clinical studies reported that NER-deficient cells were more resistant to trabectedin than their NERproficient counterparts [8, 9, 11, 12, 15].

apb5@cornell.edu) Published on WWW 19 January 2000 SUMMARY The ability to polarize is a fundamental property of cells.

The resulting blood test report by Dr Irons described and contained drawings of the abnormal red cells (Fig 2) and the photomicrographs, showing irreversibly sickled cells, leave little doubt that the diagnosis was SS disease.

Extension of life-span by introduction of telomerase into normal human cells.

The aim of the current study was to analyze the involvement of methyl-CpG binding proteins (MBDs) and histone modifications on the regulation of CD44, Cyclin D2, GLIPR1 and PTEN in different cellular contexts such as the prostate cancer cells DU145 and LNCaP, and the breast cancer cells MCF-7.