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TempVapo 100%

AChE inhibitor Sedative Antipyretic >

https://www.fichier-pdf.fr/2013/11/06/tempvapo/

06/11/2013 www.fichier-pdf.fr

Central fatigue and neurotransmitters, can thermoregulation be manipulated 98%

5-HT reuptake inhibitor NA reuptake inhibitor DA reuptake inhibitor Psychostimulant drug a1adrenergic agonist DA/NA reuptake inhibitor DA/NA reuptake inhibitor 5-HT/NA reuptake inhibitor 5-HT reuptake inhibitor 5-HT reuptake inhibitor NA reuptake inhibitor 5-HT reuptake inhibitor 5-HT reuptake inhibitor 5-HT2A/2C antagonist Pizotifen Men, n 5 8 Pannier et al.

https://www.fichier-pdf.fr/2012/01/06/central-fatigue-and-neurotransmitters-can-thermoregulation-be-manipulated/

06/01/2012 www.fichier-pdf.fr

EXPO 3 TD PH CELL 98%

danielle.burger@hcuge.ch Introduction Abstract Deregulation of the production of IL-1β and its natural inhibitor, the secreted form of IL-1 receptor antagonist (sIL-1Ra), plays an important role in the pathogenesis of chronic inflammatory diseases such as rheumatoid arthritis and multiple sclerosis.

https://www.fichier-pdf.fr/2017/09/28/expo-3-td-ph-cell/

28/09/2017 www.fichier-pdf.fr

Gagaoua et al. 2012 Serpins as biomarkers of meat tenderness 97%

In human, the only one other natural caspase inhibitor identified so far was the proteinase inhibitor 9 (PI9) which inhibits weakly and slowly caspase 1 with a kass of 7 × 102 M–1·s–1 suggesting that it will not be Published Online October 2012 in SciRes.

https://www.fichier-pdf.fr/2013/03/13/gagaoua-et-al-2012-serpins-as-biomarkers-of-meat-tenderness/

13/03/2013 www.fichier-pdf.fr

Chen 2006 94%

A selective, irreversible, second-generation MAO-B inhibitor Jack J.

https://www.fichier-pdf.fr/2011/10/04/chen-2006/

04/10/2011 www.fichier-pdf.fr

cocaine.piperidine-based.analogs.sar-2 93%

However, clinical trials would suggest that the use of SSRI alone would not likely result in significant efficacy for the treatment of cocaine withdrawal.10 Yet, there has been some reported success in polytherapy (combination of DA reuptake inhibitor and 5-HT releaser) in recent studies for cocaine withdrawal therapy.11 The pilot studies conducted using such a polytherapeutic approach report little to no side effects associated with the combination of DA reuptake inhibitor and 5-HT releaser regimen.

https://www.fichier-pdf.fr/2009/06/01/54xoxk9/

01/06/2009 www.fichier-pdf.fr

Article-PUGG-AVK-Drugs-and-Aging-Octobre-2013 91%

Proton pump inhibitor use was more frequent in the lower TTR categories, although this association did not reach M.

https://www.fichier-pdf.fr/2017/08/03/article-pugg-avk-drugs-and-aging-octobre-2013/

03/08/2017 www.fichier-pdf.fr

Antimicrobial properties of extracts regions of Tunisia 88%

Serial twofold dilutions of inhibitor were prepared in 96-well polystyrene microplates (Becton Dickinson Labware, Lincoln Park, NJ) containing 150 mL/well of TSBYE.

https://www.fichier-pdf.fr/2013/09/07/antimicrobial-properties-of-extracts-regions-of-tunisia/

07/09/2013 www.fichier-pdf.fr

Antidepressants- Marketing & Lobbying & PR 87%

Marketing and corporate communication : antidepressants Communication marketing :

https://www.fichier-pdf.fr/2013/09/13/antidepressants-marketing-lobbying-pr/

13/09/2013 www.fichier-pdf.fr

Pathophysiologie nitrite 84%

Systemic administration of the NO synthase inhibitor N-nitro-L-arginine methyl ester demonstrated a significant reduction of mean CSF nitrite production (0.95 versus 6.0 mM in controls;

https://www.fichier-pdf.fr/2011/09/27/pathophysiologie-nitrite/

27/09/2011 www.fichier-pdf.fr

GuidelinesAnxiety 81%

Panic disorder Selective Serotonin Reuptake Inhibitors (SSRIs) Citalopram Escitalopram Fluoxetine Fluvoxamine Paroxetine Sertraline Serotonin Norepinephrine Reuptake Inhibitors (SNRIs) Venlafaxine Duloxetine Tricyclic Antidepressants Amitriptyline Clomipramine Imipramine Calcium Channel Modulators Pregabalin Gabapentin MAO Inhibitors Phenelzine Reversible Inhibitor of Monoaminoxidase A (RIMA) Moclobemide Benzodiazepines Alprazolam Clonazepam Diazepam Lorazepam Atypical Antipsychotics Quetiapine Risperidone Tricyclic Anxiolytic Opipramol Azapirone Buspirone Noradrenergic and specific serotoninergic antidepressant (NasSA) Mirtazapine Antihistamine Hydroxyzine 20–60 10–20 20–40 100–300 20–60 50–150 (A;

https://www.fichier-pdf.fr/2013/08/20/guidelinesanxiety/

20/08/2013 www.fichier-pdf.fr

Diagnosis and management of Raynaud's Sd 78%

10.1136/bmj.e289 (Published 7 February 2012) Page 2 of 8 CLINICAL REVIEW Summary points Raynaud’s phenomenon is caused by episodic vasospasm and ischaemia of the extremities, particularly the digits, in response to cold or emotional stimuli Attacks comprise a colour change in extremities from white (ischaemia), to blue (deoxygenation), and then to red (reperfusion) Primary Raynaud’s phenomenon is an exaggerated response to stimuli, with no known underlying cause Secondary Raynaud’s phenomenon is usually caused by connective tissue disease and patients are more likely to develop tissue damage Nifedipine is currently the only drug licensed for use in Raynaud’s phenomenon Key areas of ongoing research include a topical nitroglycerin and a rho kinase inhibitor (vasodilator) Sources and selection criteria We searched the Cochrane Library and PubMed (2001-11) using the term “Raynaud’s”.

https://www.fichier-pdf.fr/2012/04/03/diagnosis-and-management-of-raynaud-s-sd/

03/04/2012 www.fichier-pdf.fr

10-Moron-JNeurosci2002 73%

We have tested this hypothesis by comparing the effects of inhibitors selective for the three monoamine transporters with those of a nonspecific inhibitor, cocaine, on uptake of 3H-dopamine into synaptosomes from frontal cortex, caudate nucleus, and nucleus accumbens from wild-type, NET, and dopamine transporter (DAT) knock-out mice.

https://www.fichier-pdf.fr/2011/09/28/10-moron-jneurosci2002/

28/09/2011 www.fichier-pdf.fr

D 250 E serie II 73%

— Body-up Protection prevents the transmission from shifting above a programmed gear if the hoist lever is not in “float.” — Downshift inhibitor.

https://www.fichier-pdf.fr/2011/08/08/d-250-e-serie-ii/

08/08/2011 www.fichier-pdf.fr

Khodosevichet al 2009 72%

PKCζ pseudosubstrate inhibitor myristoylated, Rac1 inhibitor, Akt inhibitor X, Clostridium difficile Toxin A, Raf1 inhibitor and rapamycin (Calbiochem, Germany);

https://www.fichier-pdf.fr/2010/11/27/khodosevichet-al-2009/

27/11/2010 www.fichier-pdf.fr

08.12.15 9H00-10H00 DUPONT (cours 2) 69%

Thrombin activable fibrinolysis inhibitor D) Traitements VI) Dégradation de la fibrine VII) Hémostase :

https://www.fichier-pdf.fr/2015/12/20/08-12-15-9h00-10h00-dupont-cours-2/

20/12/2015 www.fichier-pdf.fr

modif cell nitestinale ap chir baria 2017 pharma 68%

Addition of bile acids increased alimentary limb glucose uptake, through a SGLT1 inhibitor (phlorizin)-sensitive mechanism [32].

https://www.fichier-pdf.fr/2018/06/24/modif-cell-nitestinale-ap-chir-baria-2017-pharma/

24/06/2018 www.fichier-pdf.fr

Introduction et physiopathologie20123 67%

El biaze CHU Fès 4 Mécanisme d’action de l’inflammation REPARATION Anti protéases Anti oxydants DESTRUCTION Balance Protéases-antiprotéases Service de Pneumologie CHU Hassan II Destruction Réparation Protéases (secrétion macrophages++) Anti-Protéases Serine proteinases α1-Antitrypsin Neutrophil elastase α1-Antitrypsin Cathepsin G Secretory leukoprotease inhibitor Proteinase 3 Elafin Cysteine proteinases Cystatins Cathepsins B, K, L, S Matrix metalloproteinases Tissue inhibitor of MMP (TIMP1–4) MMP-8, MMP-9, MMP-12 Protéases Oxydants Pr.

https://www.fichier-pdf.fr/2012/03/26/introduction-et-physiopathologie20123/

26/03/2012 www.fichier-pdf.fr

epigenetic 67%

cytidine analogue zebularine – a stable DNA methylation inhibitor that has minimal toxicity in vitro and in vivo, is an effective inhibitor of p15INK4b methylation and cell growth in human AML and the results of a study of Scott et al.

https://www.fichier-pdf.fr/2010/10/15/epigenetic/

15/10/2010 www.fichier-pdf.fr

2-Rocha-Nat1998 66%

The accumbens, olfactory tubercle, sepaddition of the SERT inhibitor alaprotum, and to a lesser degree in cortical regions.

https://www.fichier-pdf.fr/2011/09/28/2-rocha-nat1998/

28/09/2011 www.fichier-pdf.fr

2 65%

https://www.fichier-pdf.fr/2017/02/13/2/

13/02/2017 www.fichier-pdf.fr

Laroche-Italiano 2017 JHO rucaparib bmy table 2 65%

Oncology (2017) 10:84 DOI 10.1186/s13045-017-0451-x RAPID COMMUNICATION Open Access Activity of trabectedin and the PARP inhibitor rucaparib in soft-tissue sarcomas Audrey Laroche1,2, Vanessa Chaire1,2, François Le Loarer2,3, Marie-Paule Algéo4, Christophe Rey1,2, Kevin Tran1,2, Carlo Lucchesi1,2 and Antoine Italiano1,2,4* Abstract Background:

https://www.fichier-pdf.fr/2017/05/10/laroche-italiano-2017-jho-rucaparib-bmy-table-2/

10/05/2017 www.fichier-pdf.fr