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Otherwise, market outcomes involve underproduction of goods or services that entail positive externalities or overproduction in the case of negative externalities.
Major sources of oxidative stress during diabetes include glucose autooxidation, overproduction of ROS by mitochondria, nonenzymatic glycation, and the polyol pathway [38, 39].
Efrén Córdova, “Some Reflections on the Overproduction of International Labour Standards”, (1993) 14 Comparative Labour Law Journal 138.
by devaluating their currencies, on one hand it would cancel all the devaluation positive effects, and would lead to an overproduction of money and in fine to a global rise of prices.
Fibroblasts in scleroderma are heterogeneous in terms of collagen synthesis.42 Overproduction of collagen is due to enhanced transcription or increased stability of collagen-specific messenger RNA.43 Upregulated transcription of collagen genes in scleroderma cells is autonomous and maintained in vitro over several passages.44 Fibroblasts in scleroderma can convert to myofibroblasts,38 and they overexpress several cytokines (e.g., transforming growth factor β [TGF-β] and monocyte chemoattractant protein 1) and TGF-β receptors.45 These findings underscore the role of autocrine loops in sustaining the fibrotic reaction.
inhibition of Cln1p or Cln2p blocks emergence, whereas overproduction of either G1 cyclin hyperpolarizes growth.
In sepsis, eNOS may be dysfunctional, which results not only in impaired perfusion and endothelial reactivity but also in overproduction of reactive oxygen species, including peroxynitrite.77 Modulation of eNOS, enabling NOS to locally produce NO could thus be beneficial for tissue perfusion but also for cellular function.
The aim of this study was to investigate the effect of overproduction of GH in the CNS on food intake, body fat mass, insulin sensitivity, and subsequent alterations in lipoprotein metabolism.